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For example, Corson et al. However, the results from the experts’ consensus provided detailed information about dose-equivalents at many levels low dose, medium dose, high dose, allowing a comprehensive view of dosage equivalents over a wide range.
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cheap Finpecia Woods’ chlorpromazine equivalent was based primarily on Comprare Risperdal Online placebo-controlled fixed-dose study by Arvinitis et al. Our chlorpromazine equivalent, by contrast, may be more in line with the findings of a placebo-controlled study by Small et al.
Davis and Chen used both studies in their meta-analysis when creating a dose response curve for quetiapine, but the Small study suggested a near-maximal response at a dose 100 mg higher than in the Arvinitis study. Comparison with the Davis equivalents for the older antipsychotics is also informative. In general, the two methods are surprisingly close, despite the differing ways in which they were derived.
In Comprare Risperdal Online cases, the expert-derived equivalents are higher 1. However, apart from trifluoperazine, Comprare Risperdal Online, they are close, suggesting that the expert-derived values are likely to be reasonably accurate. PET studies of receptor binding, principally evaluating D2 receptor Comprare Risperdal Online using C 11 raclopride, have substantially expanded our knowledge about how to balance dose ranges to maximize efficacy and minimize side effects 14, 15, 16 and 17. It is difficult to extrapolate from this work to equivalency coefficients, however, because most of this work examines only one aspect of pharmacologic efficacy— ability to block dopamine type 2 receptors—whereas most of the newer medications are believed to exert their therapeutic effects through pharmacologic profiles that affect other receptors as well, particularly serotonin 5HT2A receptors.
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